27 results
diagnosis differential management algorithm rheumatology systemic oncology aplastic erythematosus generalized hemolytic lupus myelodysplastic pancytopenia pruritus sle thrombocytosis workup activation agglutinin
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Secondary ... suspect underlying hematologic ... Diagnosis and Treatment ... Matthew Ho, MD ... #HES #Hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Hepatopulmonary syndrome ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia •
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... Muehrcke's Lines - Transverse ... • Nephrotic syndrome ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... #MDS #Diagnosis ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Differential Diagnosis Secondary ... malignancies • Anemia ... Myelodysplastic syndrome ... #hematology #secondary
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... - Hemolytic anemia ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Treatment: • Consider ... Can progress to MDS ... • Associated PNH ... diagnosis #management #treatment ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
PNH 2. ... HLH syndrome 5. ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... Diagnosis #Algorithm #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... hemoglobinuria (PNH ... differential #diagnosis #hematology ... #anemia
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