12 results
diagnosis rheumatology differential management erythematosus lupus signs sle symptoms systemic anemia aplastic autoimmune behcet brain cauda caudaequina cerebritis disease equina
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... +PNS+GI+Endocrine ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... 30% present w/ CNS ... , may also see skin ... @AnnKumfer #CNS
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... Other brainstem syndromes ... Many others • Transverse ... pain • Extra-CNS ... Manifestations #diagnosis #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... collaboration • CNS ... signs #symptoms #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... • (Peripheral eosinophilia ... : CNS manifestations ... CLL -> Invade Skin ... #Oncology #Diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... peripheral neuropathy, transverse ... • 8%-27% for CNS ... Nephrogenic DI Hematologic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... - Hepatitis, eosinophilic ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, neurologic, and ... cognitive impairment, neurologic ... Polyangiitis): • Eosinophilia ... tract, and often causes ... chorioretinitis, CNS
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
(CES) is usually ... - Emergency Causes ... myelopathy • Transverse ... stimulation of skin ... #neurology
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