126 results
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Lymphomas - Systemic ... Hypereosinophilic Syndrome ... Differential #Diagnosis #Causes ... #hematology
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
hypereosinophilic syndrome ... Hyper-lgE (Job) syndrome ... GI, lung, skin), ... B-cell lymphomas), Systemic ... ABPA), Gleich syndrome
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
, hemoptysis; +systemic ... Hypereosinophilic Syndrome ... in 40%, mild; +systemic ... , wt loss; CV, CNS ... , skin • Infectious
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... for secondary causes ... (common causes ... symptoms (eg, skin ... Differential #diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Reaction with Eosinophilia ... and Systemic Signs ... (DRESS Syndrome ... medication (in this case ... Images #Clinical #Dermatology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Reaction with Eosinophilia ... and Systemic Signs ... (DRESS Syndrome ... medication (in this case ... Images #Clinical #Dermatology
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
lung disease • Eosinophilic ... polyangiitis - Asthma. eosinophilia ... and C viruses. systemic ... and Sjogren's syndrome ... in absence of skin
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... Secondary Causes ... Hypereosinophilia #Syndrome ... #HES #eosinophilia ... #diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Reaction with Eosinophilia ... and Systemic Symptoms ... (DRESS) Syndrome ... Steroids for severe systemic ... , IVIG etc • Skin
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Amyloidosis (CVS+PNS ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology