10 results
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... Hypomagnesemia, Acute ... and lymphomas, IV ... #Causes #differential ... #diagnosis #nephrology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... (both ALL and AML ... : • IV fluids ... #TLS #oncology ... #management #UricAcid
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential # ... Diagnosis #Classification ... #Nephrology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Attempt if high ... Supportive Care: Diuresis ... #APML #diagnosis ... #management #hematology ... #oncology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
urinary losses: • High ... Renin secreting tumor ... #diagnosis #Algorithm ... #differential # ... potassium #nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
• Triggers: Diuretics ... - ACS, AKI, acute ... hydration - Hyperkalemia ... #TLS #diagnosis ... #management #hematology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • K sparing diuretics ... Transfusion reaction - Tumor ... lysis syndrome ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • K sparing diuretics ... Transfusion reaction - Tumor ... lysis syndrome ... #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diagnosis of ... irrigation • Management ... ; High-Ceiling Diuretics ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Arthritis, AS Treatment ... interferon alfa, or tumor ... exacerbations: high-dose ... #diagnosis #management