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hematology diagnosis differential management anemia algorithm microscopy smear causes atlas liver morphology oncology path pathology pathophysiology peripheral transfusion autoagglutination babesia
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Decreased RBC ... Infiltration Increased RBC ... Thalassemia • RBC ... Disorder • RBC
ABO Blood Types and Transfusion Compatibility Table A Blood Type: • RBC Antigens: A • Antibodies: Anti-B
Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens ... Compatibility #Table #hematology
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
directed donations) - RBC ... Hct of 70-80% - RBC ... plasma, a few RBC ... ofplasma, a few RBC ... Contents #Volume #Hematology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... cell, Other RBC ... Howell-Jolly bodies #RBC ... Microscopy #Pathology #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC) Morphology ... Microcytic RBC: ... disease, McLeod blood ... Bite Cell RBC: G6PD
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... 3) Internal (RBC ... - Peripheral Blood ... Smear ↑ abnormal RBCs ... Differential #Diagnosis #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(MCV): Average RBC ... wide range of RBC ... in peripheral blood ... High in acute blood ... Diagnosis #Workup #Hematology
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... #Clinical #Path ... #Blood #Smear #Microscopy ... #RBC #Autoagglutination
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... #Clinical #Path ... #Blood #Smear #Microscopy ... #RBC #Autoagglutination
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... Transfusing blood ... Blood saves lives ... studies show that PRBC ... VisualAbstract #Trials #PRBC
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