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diagnosis hematology differential treatment anemia hepatology algorithm causes criticalcare medications nephrology renal shock hemolytic hepatopulmonary liver table agglutinin antibiogram antibiotics
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
directed donations) - RBC ... Hct of 70-80% - RBC ... plasma, a few RBC ... ofplasma, a few RBC ... Volume #Hematology #Management
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Drug-associated, PCH, Evans Syndrome ... 3) Internal (RBC ... - Peripheral Blood ... Smear ↑ abnormal RBCs
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... Transfusions: Cellular blood ... disorders (DiGeorge Syndrome ... #Irradiation #RBC ... Hematology #BloodBank #Management
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... • Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... coagulopathy (DIC) #RBC
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
urine • 1ml blood ... Hematuria: 3 or more RBC ... hematuria: - RBC ... - Dysmorphic RBC ... #renal #urine #blood
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Algorithm Normal Blood ... Neutrophils - Low RBC ... Pernicious Anemia RBCs ... Myelodysplastic Syndromes
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
↑ LDH • Anti-RBC ... type ± C3d • Blood ... Anemia #diagnosis #management
Approach to Hemorrhagic Shock PLAN FOR CONTROLLING HEMORRHAGE & ACTIVATE MASSIVE TRANSFUSION PROTOCOL • Activate massive transfusion
product faster USE BLOOD ... resuscitation with blood ... ratio, e.g. 1 RBC ... • Can use CBC ... Hemorrhagic #Shock #Management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... blasts and high WBC ... hyperviscosity syndrome ... Triggers: Diuretics, PRBC ... TLS #diagnosis #management
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