32 results
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
directed donations) - RBC ... Hct of 70-80% - RBC ... plasma, a few RBC ... ofplasma, a few RBC ... Volume #Hematology #Management
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
↑ LDH • Anti-RBC ... type ± C3d • Blood ... Anemia #diagnosis #management ... #treatment #rheumatology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... Transfusions: Cellular blood ... #Irradiation #RBC ... #Blood #Transfusion ... Hematology #BloodBank #Management
Approach to Hemorrhagic Shock
PLAN FOR CONTROLLING HEMORRHAGE & ACTIVATE MASSIVE TRANSFUSION PROTOCOL
 • Activate massive transfusion
product faster USE BLOOD ... resuscitation with blood ... ratio, e.g. 1 RBC ... • Can use CBC ... Hemorrhagic #Shock #Management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Leukocyte reduced RBC ... Gamma-irradiated RBC ... Volume Reduced RBC ... • Washed RBC ... Transfusions #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Triggers: Diuretics, PRBC ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment ... TLS #diagnosis #management
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
, Severe pHTN, Constrictive ... • Hypovolemic: Blood ... Dehydration Shock Treatment ... criticalcare #algorithm #treatment ... #management
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
Clinical Management ... begin packed red blood ... cell (PRBC) infusion ... hemorrhage, immediate PRBC ... • Begin PRBC
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
anorexia, ARDS ​• RBC ... coccobacillus within the RBCs ... TREATMENT: ​• Acute ... Fever #diagnosis #management
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
Pharmacological Treatment ... Alpha agonist incr blood ... Syndrome #Nephrology #Management ... #Pharmacology # ... Medications #Treatment