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diagnosis differential treatment rheumatology dermatology oncology causes microbiology hepatology algorithm blood chagas classification clinical leukemia trypanosomiasis vasculitis alopecia american anemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... pancreatitis, Post-surgical ... Others: Asplenia/post-splenectomy
Adjuvant therapies in critical care: steroids to treat infectious diseases - Severe Community Acquired Pneumonia
steroids to treat infectious ... diseases - Severe ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Management #Treatment
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
other cancers: Most ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... Internal (RBC) - Infections ... Peripheral Blood Smear ... Differential #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Cold-induced symptoms - most ... IgM) • Blood smear ... Polyclonal IgM post ... hemolytic #anemia #hematology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Diagnosis • Infection ... Lemierre's syndrome ... Malignancy: - Hematologic ... carcinoma • Non-infectious ... arteritis is prob the most
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
Urinothorax Exudate - Infectious ... Collagen vascular disease ... Gastrointestinal disease ... • Post-CABG ... Diagnosis #Algorithm #Hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... chemotherapy, anti-CD20 (PTLD ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... disorders • Shear ... #treatment #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... antibiotics are the most ... spherocytosis) • Infections ... differential #diagnosis #hematology
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