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differential treatment causes hematology microbiology oncology algorithm infections rheumatology classification disease fever neurology signs workup criticalcare dermatology symptoms chagas checklist
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... develop leukostasis syndrome ... • Peripheral smear ... • Tumor lysis syndrome ... Hematology #Oncology #Diagnosis
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Post-Transplantation ... , intensity of induction ... #Post #Transplantation ... Disorders #oncology #diagnosis ... #management #transplant
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... weeks without infection ... Diagnosis: • ... • Peripheral smear ... • Richter’s Syndrome
Disseminated Gonococcal Infection - Diagnosis and Management Summary Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
Management Summary ... Purulent Arthritis Syndrome ... : • Most patients ... #Management #Microbiology ... #InfectiousDiseases
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... lymphoid malignancy (CLL ... IgM) • Blood smear ... Polyclonal IgM post ... malignancies -> CLL
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Peripheral Smear ... Kawasaki, Nephrotic syndrome ... pancreatitis, Post-surgical ... #Differential #Diagnosis
CENTRAL FACIAL / NASAL LESIONS Bacteria: • Leprosy (saddle nose deformity) • Tuberculosis (lupus vulgaris)l • Endemic
Endemic treponemal infection ... Invasive mold infection ... Malignancy: • NK cell ... Trigeminal trophic syndrome ... #diagnosis #infectiousdiseases
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... antibiotics are the most
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome ... macroglobulinemia (most ... transformation (CML ... #Differential #Diagnosis ... #Treatment #Management
Causes of Severe Aortic Regurgitation - Differential Diagnosis Acute: • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
- Differential Diagnosis ... Valve Dysfunction, Post ... Salmonella), Giant Cell ... Ehlers-Danlos Syndrome ... #Differential #Diagnosis
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