61 results
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Post-Transplantation ... hematopoietic cell ... , intensity of induction ... #Post #Transplantation ... oncology #diagnosis #management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Peripheral Smear ... Kawasaki, Nephrotic syndrome ... pancreatitis, Post-surgical ... Others: Asplenia/post-splenectomy
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
: • Most common ... weeks without infection ... • Peripheral smear ... • Richter’s Syndrome ... leukemia • Sezary syndrome
CENTRAL FACIAL / NASAL LESIONS
Bacteria:
 • Leprosy (saddle nose deformity)
 • Tuberculosis (lupus vulgaris)l
 • Endemic
Endemic treponemal infection ... Malignancy: • NK cell ... Trigeminal trophic syndrome ... #diagnosis #infectiousdiseases ... #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... IgM) • Blood smear ... Polyclonal IgM post ... malignancies -> CLL ... younger pts) Differential
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
Diagnosis and Management ... Arthritis-Dermatitis syndrome ... Purulent Arthritis Syndrome ... : • Most patients ... #Microbiology #InfectiousDiseases
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... macroglobulinemia (most ... transformation (CML ... #Causes #Differential ... Diagnosis #Treatment #Management
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Regurgitation - Differential ... Valve Dysfunction, Post ... Salmonella), Giant Cell ... Arteritis, Behcet Syndrome ... Ehlers-Danlos Syndrome
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... antibiotics are the most ... Extravascular #Causes #differential
Blurry vision in a patient with HIV/AIDS
Anterior Segment:
 • Herpes zoster ophthalmicus
 • Keratitis (HSV, Staph,
• Choroidal infections ... syphilis) *Most ... with lower CD4 cell ... vision #HIVAIDS #InfectiousDiseases ... Anterior #Posterior #Differential