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differential algorithm treatment hematology microbiology clinical dermatology nephrology neurology oncology rheumatology workup disease classification fever gastroenterology acute cardiology lung pulmonary
Rapidly Growing Mycobacterial Infections • Mycobacterium abscessus - Is the most pathogenic and the most likely
Mycobacterial Infections ... likely to cause ... pulmonary infection ... Mycobacterium #diagnosis ... #differential #infectiousdiseases
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... Hematology #Oncology #Diagnosis
Causes of Acute Onset Fever - Differential Diagnosis Algorithm Viral: • Rhinovirus • Influenza Virus • Parainfluenza
Coronavirus • HIV Infectious ... Organ Specific Infection ... Respiratory Tract Infection ... Urinary Tract Infection ... Neuroleptic malignant syndrome
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Most invasive infections ... are caused by members ... Rhinosinusitis, CNS infection ... , Disseminated infection ... systemic vori Infectious
Ear Pain (Otalgia) - Differential Diagnosis Framework Primary Otalgia - Pain that originates from the ear
associated with infection ... by bacterial infections ... (90%), Fungal infections ... • Dental infections ... • Dental infections
CENTRAL FACIAL / NASAL LESIONS Bacteria: • Leprosy (saddle nose deformity) • Tuberculosis (lupus vulgaris)l • Endemic
Endemic treponemal infection ... Invasive mold infection ... Trigeminal trophic syndrome ... Central #Lesions #infections ... #diagnosis #infectiousdiseases
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Acquired HLH: • Infections ... Still disease, Infection ... Drugs, Unknown cause ... Etiological+++: Anti-infectious
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) (e.g. lupus, CLL ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... Check For: • Infections ... Polyclonal IgM post ... infectious setting
Causes of Severe Aortic Regurgitation - Differential Diagnosis Acute: • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Causes of Severe ... - Differential Diagnosis ... Valve Dysfunction, Post ... - Leaflet: • Infection ... Inflammatory: Infectious
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