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diagnosis hematology differential oncology treatment causes microbiology workup anesthesia anesthesiology chronic fever gastroenterology intraoperative lymphocytic mds myelodysplastic neurology 1 agglutinin
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... • Peripheral smear
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... weeks without infection ... • Peripheral smear ... • Richter’s Syndrome ... syndrome • Smoldering
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome ... macroglobulinemia (most ... transformation (CML ... Hydroxyurea - Leukemia ... Diagnosis #Treatment #Management
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... Check For: • Infections ... Polyclonal IgM post ... infectious setting
Disseminated Gonococcal Infection - Diagnosis and Management Summary Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
Disseminated Gonococcal Infection ... symptomatic genital infection ... : • Most patients ... Disseminated #Gonococcal #Infection ... #Microbiology #InfectiousDiseases
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... Overview: • Most ... • Peripheral smear ... Complications: 1) Infection ... hemeonc #diagnosis #management
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute infection ... sarcoidosis) • Post-splenectomy ... Myelodysplastic syndrome ... Chronic myeloid leukemia ... (CML) - Dr.
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Diagnosis • Infection ... Lemierre's syndrome ... malignancies: Lymphoma, Leukemia ... tumors: Renal cell ... carcinoma • Non-infectious
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... transformation to acute leukemia ... Allogeneic stem cell ... Myelodysplastic #Syndrome
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- DDX: - Infection ... to the knee Infectious ... Behcet Disease Post-Infectious ... Seronegative Reactive Syndrome ... Hematologic - Leukemia
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