62 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... Malaise, bleeding, infections ... extramedullary disease ... pain, bleeding, infections ... bruising, bleeding, infection
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... - Due to Viral infection ... Polyclonal - Viral Infection ... Check For: • Infections ... infectious setting
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
steroids to treat infectious ... diseases - Severe ... respiratory distress syndrome ... #Infections #Pharmacology ... #Management #Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Acquired HLH: • Infections ... , Infection under ... Etiological+++: Anti-infectious ... chemotherapy, anti-CD20 (PTLD
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Peripheral Smear ... Kawasaki, Nephrotic syndrome ... TPO, TPO-RA • Infections ... : Chronic infections ... bacterial and viral infections
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... history of recurrent infections ... • Infectious ... community-acquired infections ... Malignancies • Chronic infections
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Valve Dysfunction, Post ... - Leaflet: • Infection ... Inflammatory: Infectious ... Salmonella), Giant Cell ... Ehlers-Danlos Syndrome
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
Most invasive infections ... Rhinosinusitis, CNS infection ... , Disseminated infection ... systemic vori Infectious ... Diseases Fellows
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Diagnosis • Infection ... Lemierre's syndrome ... tumors: Renal cell ... carcinoma • Non-infectious ... arteritis is prob the most