29 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Peripheral Smear ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... pancreatitis, Post-surgical
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Myelofibrosis Infectious ... disorders • Celiac disease ... Tissue Damage: • Post-op ... effect following treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... chemotherapy, anti-CD20 (PTLD ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... thrombocythemia), Autoimmune disease ... disorders • Shear ... #treatment #hematology ... #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold-induced symptoms - most ... IgM) • Blood smear ... Polyclonal IgM post ... younger pts) Differential ... hemolytic #anemia #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... fraction < 20% Differential ... Diaqnoses: • Infectious ... #diagnosis #management ... #treatment #rheumatology
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
Diagnostic Approach and Differential ... Diagnosis The most ... of underlying disease ... perforation), TB smear ... #Diagnosis #hepatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... Complications: 1) Infection ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... trypanosomiasis) is an infectious ... family Route of infections ... positive serology, smear ... thick peripheral smears
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... (KD) is the most ... cæxist with other infections ... KD #vasculitis #rheumatology ... #treatment