24 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... chemotherapy, anti-CD20 (PTLD ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Diagnosis and Management ... GrepMed Handbook Clinical ... up to 10w post-ABx ... equivocal • CT A/P: Assess ... continue Tx for 7d post-Abx
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common ... Lung Abscess - Clinical ... Differential Diagnosis ... #pulmonary #differential
Candidemia Workup and Management - IDSA Guidelines
1) Antibiotics
 • Empiric: Echinocandins (e.g. micafungin) for most patients
Candidemia Workup and Management ... - IDSA Guidelines ... micafungin) for most ... or TEE unless clinical ... #candidiasis #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • Infectious ... Disease #diagnosis #management ... #treatment #rheumatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
emboli • Lung abscess ... characteristic features Clinical ... Tuberculosis Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... presentation, and most ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
emboli • Lung abscess ... characteristic features Clinical ... Tuberculosis Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Overview: • Most ... immunophenotype Clinical ... Complications: 1) Infection ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
skin necrosis (at injection ... Diagnosis: • Clinical ... Bayesian approach for post-test ... non-heparin A/C if clinical ... #Treatment #Hematology