28 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... lesions • Discoid ... #rashes #differential ... #diagnosis #rheumatology
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
weeks - Typical skin ... rash: maculopapular ... non-pruritic, salmon-pink rash ... polyarteritis nodosa #AdultOnset ... #Major #Minor #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... reticularis Differential ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Cranial nerve lesions ... pain (20%) Renal disease ... symptoms #diagnosis #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... maculopapular rash ... BrighamChiefs #AdultOnset ... #AOSD #rheumatology ... #diagnosis #management
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
Pustular Skin Lesions ... - Differential ... Generalized itchy rash ... #Lesions #Differential ... #Diagnosis #Dermatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... lesions that result ... #Diagnosis #hematology ... #rheumatology #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... test (this is a skin ... ) Differential Diagnosis ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Skin manifestations ... for refractory lesions ... or refractory lesions ... Syndrome #Treatment #management ... #pharmacology #rheumatology