15 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... tests, Low Platelets ... #Thrombocytopenia ... AFLP #obstetrics #hematology ... #diagnosis #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... tests, Low Platelets ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... - Differential ... Matthew Ho, MD PhD ... Diagnosis #Algorithm #hematology ... #platelets
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... chain IIA • Thrombocytopenia ... Defects #comparison #table ... #differential # ... diagnosis #hematology
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
for Causes of Thrombocytopenia ... Enlarged Spleen L - Liver ... Mnemonic #Acronym #Thrombocytopenia ... #Differential # ... Diagnosis #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... : INR/PT, aPTT(liver ... or if a primary hematologic ... #Differential # ... Causes #Workup #hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis Table ... • Thrombotic Thrombocytopenic ... Matthew Ho, MD PhD ... Microangiopathy #TMA #hematology ... #differential #
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Pregnancy Intrahepatic ... enzymes, and Low Platelets ... features: Hemolysis, Thrombocytopenia ... #hepatology #obstetrics ... hepatitis #comparison #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... Primary Causes: - Thrombocytopenia ... deficiency • Liver ... #Diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Diagnosis Algorithm Thrombocytopenia ... Sequestration Disordered Platelet ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology