15 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Parenchyma • Infectious ... C, A, E, B, D, EBV ... Other: NAFLD, Autoimmune ... #Injury #Differential
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-mitochondrial (AMA ... biliary cirrhosis (PBC ... Celiac disease Anti-GBM ... diseases #diagnosis #table ... #rheumatology #
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Grafts, Valves, AS ... Membrane): - Autoimmune ... Drug-associated, PCH ... Defects, Drugs, Liver ... Internal (RBC) - Infections
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Injury: • Infectious ... HBV, HCV, HEV, EBV ... Celiac disease • Autoimmune ... : Autoimmune hepatitis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
, autoimmune disorder ... - Mycoplasma, EBV ... CLL (older) • Autoimmune ... younger pts) Differential ... Disorders Such As
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... , Autoimmune diseases ... Etiology: - Infections ... Pylori) - Autoimmune ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... fraction < 20% Differential ... Diaqnoses: • Infectious ... Coxsackie, CMV, EBV ... management #treatment #rheumatology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... /l is regarded as ... rav7ks #CNS #Infections ... #differential #
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... • Symptoms: AMS ... symptoms such as ... effect/Edema • EBV ... #differential #
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Corticosteroid use • Autoimmune ... tachycardia or fever ... science/article/abs ... /pii/S0735675715001795 ... #Bandemia #differential