28 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... C, A, E, B, D, EBV ... , Alpha-1 Antitrypsin ... PBC, 1° PSC, Cystic ... #Injury #Differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... fraction < 20% Differential ... Coxsackie, CMV, EBV ... diagnosis #management #treatment ... #rheumatology
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Hyponatremia: 1) ... history (cardiac, liver ... , renal disease) ... history #Diagnosis #EM ... #Algorithm #Ddxof
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Drug-induced SLE Anti-Jo-1 ... Dermatomyositis Anti-LKM (liver ... biliary cirrhosis (PBC ... Anti-GBM - Goodpasture's ... diagnosis #table #rheumatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... HBV, HCV, HEV, EBV ... - Half-life: 1 ... • Cirrhosis: > 1 ... injury #hepatitis #differential
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
Ulceroglandular: Fever ... Culture & GS, PCR ... Treatment: ... : 1) Ciprofloxacin ... #infectiousdiseases
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... - Pel-Ebstein fever ... (HIV, EN, HTLV-1, ... involvement Differential ... #hematology
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
Mild: Malaise, fever ... • Severe: Only 1% ... • Treatment: ... PCR not useful for ... #Microbiology #InfectiousDiseases
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... #summary #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Fever/Chills/Joint ... HSV, Varicella, EBV ... Acute rheumatic fever ... Effusions #causes #differential