537 results
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
O2 is inspired) PAO2 ... hypoxia) - Low PaO2 ... Low SvO2 → Low PaO2 ... #differential #diagnosis ... #causes #pathophysiology
Markers of Organ Dysfunction in Severe Sepsis 
Altered consciousness 
Confusion 
Psychosis 

Tachycardia 
Hypotension 
Altered CVP 
Altered
Altered CVP Altered PAOP ... Tachypnoea PaO2 ... 90% PaO2/FiO2 300% ... Protein C #Diagnosis ... #CriticalCare #Diagnosis
Respiratory Oxygenation Cycle - Pathophysiology
PO2 and PCO2

By @rev.med

#Respiratory #Oxygenation #Cycle #circulation #pathophysiology
Oxygenation Cycle - Pathophysiology ... PO2 and PCO2 By ... #circulation #pathophysiology
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... /0.8)] - PaO2 Simplified ... /0.8)] - PaO2 Normal ... #differential #diagnosis
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
- Positive: CD2 ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... Rarely can be CD4 ... hemepath #pathology #diagnosis
Hepatopulmonary Syndrome
HPS - Diagnosis:
 1. Patients with liver disease
 2. Alveolar-arterial oxygen gradient (AaP02) >15 mmHg
Syndrome HPS - Diagnosis ... Moderate HPS: ≥ 60 PaO2 ... Severe HPS: ≥ 50 PaO2 ... Very severe HPS: PaO2 ... Hepatopulmonary #Syndrome #diagnosis
ABG vs VBG: Arterial vs Venous Blood Gases

ABG
PROS: Tells you exactly what the arterial environment looks
looks like (pH, PaCO2 ... Comparison #pH #pCO2 ... #Diagnosis #Differences
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
+ (↑ pH) • ↓ PCO2 ... + (Acid) • ↑ PCO2 ... Dissociation #Curve #pathophysiology
Oxygen Delivery Equation
DO2 = CO x {(1.39 x Hb x sO2) + (PaO2 x 0.03)}
DO2 =
x Hb x sO2) + (PaO2 ... effective hemoglobin PaO2 ... in your hands = PaO₂ ... Delivery #Equation #pathophysiology
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis

pH ↓ pCO2 ↓ -
Alkalosis pH ↓ pCO2 ... acidosis pH ↑ pCO2 ... alkalosis pH ↑ pCO2 ... alkalosis pH ↓ pCO2 ... Interpretation #AcidBase #Diagnosis