153 results
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
O2 is inspired) PAO2 ... reaches the alveoli) PaO2 ... Low SvO2 → Low PaO2 ... sepsis) - High PaO2 ... diagnosis #causes #pathophysiology
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... /0.8)] - PaO2 Normal ... Hypoventilation Syndrome ... Hepatopulmonary Syndrome
Respiratory Oxygenation Cycle - Pathophysiology
PO2 and PCO2

By @rev.med

#Respiratory #Oxygenation #Cycle #circulation #pathophysiology
Oxygenation Cycle - Pathophysiology ... PO2 and PCO2 By ... #circulation #pathophysiology
COVID-19 Life Cycle

#COVID19 #LifeCycle #Timeline #Pathophysiology #Diagnosis
Cycle #COVID19 #LifeCycle ... #Timeline #Pathophysiology
Hepatopulmonary Syndrome
HPS - Diagnosis:
 1. Patients with liver disease
 2. Alveolar-arterial oxygen gradient (AaP02) >15 mmHg
Hepatopulmonary Syndrome ... Moderate HPS: ≥ 60 PaO2 ... Severe HPS: ≥ 50 PaO2 ... Very severe HPS: PaO2 ... Hepatopulmonary #Syndrome
Platypnea-Orthodeoxia Syndrome on Physical Exam
The case of a patient with a diagnosis of cirrhosis and platypnea-orthodeoxia
Platypnea-Orthodeoxia Syndrome ... platypnea-orthodeoxia syndrome ... there is a drop in SaO2 ... to 90% (and in paO2 ... #Orthodeoxia #Syndrome
Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS) 
- Respiratory symptoms must have begun within one
Respiratory Distress Syndrome ... inspired oxygen (PaO2 ... - 200 mm Hg < PaO2 ... - 100 mm Hg < PaO2 ... Respiratory #Distress #Syndrome
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
+ (↑ pH) • ↓ PCO2 ... + (Acid) • ↑ PCO2 ... Dissociation #Curve #pathophysiology
Oxygen Delivery Equation
DO2 = CO x {(1.39 x Hb x sO2) + (PaO2 x 0.03)}
DO2 =
x Hb x sO2) + (PaO2 ... effective hemoglobin PaO2 ... in your hands = PaO₂ ... Delivery #Equation #pathophysiology
Understanding & Treating ARDS - Acute Respiratory Distress Syndrome

•  Timing - within one week of
Respiratory Distress Syndrome ... Impaired Oxygenation PaO2 ... Distress #Acute #Syndrome