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diagnosis differential causes clinical algorithm management neurology physicalexam video cardiology nephrology pathophysiology treatment table signs comparison symptoms hematology rheumatology ophthalmology
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... /0.8)] - PaO2 Normal ... Hypoventilation Syndrome ... Hepatopulmonary Syndrome
Hepatopulmonary Syndrome HPS - Diagnosis: 1. Patients with liver disease 2. Alveolar-arterial oxygen gradient (AaP02) >15 mmHg
Hepatopulmonary Syndrome ... Moderate HPS: ≥ 60 PaO2 ... Severe HPS: ≥ 50 PaO2 ... Very severe HPS: PaO2 ... Hepatopulmonary #Syndrome
Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS) - Respiratory symptoms must have begun within one
Respiratory Distress Syndrome ... inspired oxygen (PaO2 ... - 200 mm Hg < PaO2 ... - 100 mm Hg < PaO2 ... Respiratory #Distress #Syndrome
Understanding & Treating ARDS - Acute Respiratory Distress Syndrome • Timing - within one week of
Respiratory Distress Syndrome ... Impaired Oxygenation PaO2 ... Distress #Acute #Syndrome
Platypnea-Orthodeoxia Syndrome on Physical Exam The case of a patient with a diagnosis of cirrhosis and platypnea-orthodeoxia
Platypnea-Orthodeoxia Syndrome ... platypnea-orthodeoxia syndrome ... there is a drop in SaO2 ... to 90% (and in paO2 ... #Orthodeoxia #Syndrome
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 The Berlin Definition of Acute Respiratory Distress Syndrome (ARDS) Chest imaging - Bilateral opacities—not fully explained by
Respiratory Distress Syndrome ... - 200 mm Hg < PaO2 ... - 100 mm Hg < PaO2 ... H2O - Severe - PaO2 ... Respiratory #Distress #Syndrome
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 Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... • Orthopnea - PaO2 ... Oxygenation defect - PaO2 ... supplemental oxygen if PaO2 ... hepatopulmonary #syndrome
Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
O2 is inspired) PAO2 ... reaches the alveoli) PaO2 ... Low SvO2 → Low PaO2 ... Low SvO2 → Low PaO2 ... sepsis) - High PaO2
Acute Respiratory Distress Syndrome – ARDS: Clinical Cheat Sheet An acute diffuse, inflammatory lung injury, leading to
Respiratory Distress Syndrome ... on CT or CXR ● PaO2 ... RespiratoryDistress #Syndrome
Markers of Organ Dysfunction in Severe Sepsis Altered consciousness Confusion Psychosis Tachycardia Hypotension Altered CVP Altered
Altered CVP Altered PAOP ... Tachypnoea PaO2 ... <70mmHg SaO2 < ... 90% PaO2/FiO2 300%
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