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management diagnosis hematology nephrology barre clinical differential encephalopathy guillain hepatorenal hrs lysis oncology physicalexam sclerosis tls tumor video aids als
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Prednisone 5mg/kg ... Renal Failure Treatment
Pisa Syndrome (pleurothotonus) on Physical Exam A tonic flexion of the trunk of the body to one
Pisa Syndrome (pleurothotonus ... Pathophysiology: ... Treatment: anticholinergics ... FatimahDandan #Pisa #Syndrome ... PhysicalExam #clinical #neurology
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 Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... : • Pathophysiology ... Low calcium • Treatment ... unless worrisome EKG
Hepatorenal Syndrome Treatment Volume expansion: • Albumin (typical dose = 1g/kg on day 1 +/- day
Hepatorenal Syndrome ... Treatment Volume ... typical dose = 1g/kg ... #Treatment #management ... #HRS #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... Treatment: ... Erythematosus #SLE #CNS #neurology
BRASH Syndrome B - Bradycardia R - Renal failure A - AV nodal blockade S - Shock H - Hyperkalemia Typical ECG
BRASH Syndrome ... Hyperkalemia Typical ECG ... hyperkalemia) BRASH Treatment ... • Aggressive treatment ... diagnosis #management #pathophysiology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... (both ALL and AML ... malignancies Treatments ... with Ca only if EKG ... #Tumor #Lysis #Syndrome
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
dysfunctions ( e.g ... Anorexia nervosa Treatment ... Encephalopathy • A prompt treatment ... development of Korsakoff syndrome ... Diagnosis #Management #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Pathophysiology ... of diazepam • EMG ... Treatment: • ... Diagnosis #Management #treatment ... #neurology
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