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differential erythematosus systemic activation ana antibodies antinuclear cardiology causes classification decisionaid dermatology disorders druginduced eosinophil eosinophilia hcq hydroxychloroquine levels macrophage
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... 200ng/mL Best indications ... #rheumatology # ... pharmacology #levels ... #lupus #management
Managing warfarin INR Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... #management #algorithm ... #pharmacology # ... decisionaid #cardiology #hematology ... #warfarin #dosing
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Using fluorescence ... disease (MCTD), Drug-induced ... ANA #patterns #rheumatology ... #diagnosis #differential
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Lupus Erythematosus ... Erythematosus #medications ... #drugs #pharmacology ... #differential #diagnosis ... #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
INDICATIONS FOR ... • Peripheral blood ... asthma, allergy, drug ... #Differential #diagnosis ... #hematology #eosinophilia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... Arthritis: • Joint pain ... activation and/or medications ... #Rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Algorithm Pinpoint ... lesions • Severe pain ... Immunosuppressed • New medication ... Autoimmune Vasculitis (lupus ... #dermatology #physicalexam
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... ) • Sepsis • Drug-induced ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
such as systemic lupus ... pulses, bruis, or blood ... Large Vessel: Blood ... vasculitis, and SLE ... #rheumatology #
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