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differential management syndrome pulmonary rheumatology hepatology infections infectiousdiseases classification algorithm cardiology endocarditis hepatopulmonary lung product transfusion vasculitis workup abscess antibiotic
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... of high parity blood ... Pathophysiology: 2 hit ... without other cause ... #hematology #diagnosis
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... head and neck, pancreas ... biliary, renal, lung ... concentration PET-CT ... #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Related Acute Lung ... TRALI resembles ARDS ... Extremely rare - HIV ... #Transfusion #diagnosis ... #management #hematology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... • Most common cause ... anemia • Sputum/Blood ... seen • Chest CT ... #differential #causes
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Related Acute Lung ... TRALI resembles ARDS ... Extremely rare - HIV ... #Transfusions #diagnosis ... #management #hematology
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... GAS in 30% of cases ... body site (i.e., blood ... kidneys, liver, lung ... /ARDS, coagulopathy
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... Chest CT: • Ground-glass ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Diagnosis Framework ... Disease by CD4 ... • CT: Halo sign ... Chest pain, cough, bloody ... #AIDS #pulmonary
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Criteria for Diagnosis ... : symptomatic treatment ... • Severe disease ... Oral/IV Glucocorticoids
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Infections in HIV-AIDS ... failure, COPD, Lung ... CXR +/- High res CT ... scan), CBC/diff, Blood ... Infectious Diseases
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