20 results
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... but also reduces CPP ... = dilated BV = raises ... Target CPP 60. ... Pressure #ICP #Pathophysiology
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
vast majority of cases ... pyrophosphate dihydrate (CPPD ... and/or x-ray - CPPD ... Chondrocalcinosis #Pseudogout #CPPD ... Signs #Symptoms #Pathophysiology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... Constipation, Dry ... SerotoninNorepinephrine #Inhibitors #Pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... few hours to a day ... Dehydration (up to 4-5L dry ... Abdominal pain, nausea ... DiabeticKetoacidosis #DKA #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... protein C and S Pathophysiology ... MAHA: TTP/HUS > DIC ... Treat primary cause ... Coagulation #diagnosis #causes
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... hyperglycemic crises ... , hypovolemia (dry
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
tear glands -> Dry ... salivary glands -> Dry ... inflammation tends to cause ... -> Dyspnea + dry ... RheumatoidArthritis #RA #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... cardiomyopathy, ARDS, DIC ... Hyperventilation, Dizziness, Nausea ... , Dehydration, Dry ... differential #diagnosis #causes
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
Explained Around Day ... and release LH causes ... #OvarianCycle #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... rapidly develops (DIC ... diagnosis #management #pathophysiology