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diagnosis differential signs management neurology algorithm endocrinology syndrome treatment rheumatology clinical cardiology psychiatry hematology msk secondary comparison complications table hepatology
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Parathyroid hormone–dependent ... Primary hyperparathyroidism ... Granulomatous disease ... Hypercalcemia #Causes
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 Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... Hyperthyroidism • Paget's disease ... Chronic kidney disease ... • Tertiary hyperparathyroidism ... Hypercalcemia #Causes
Hypocalcemia Laboratory Evaluation Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
hypocalcemia: - Hypoparathyroidism ... activating mutation - Parathyroid ... Chronic kidney disease ... Laboratory #Levels #Hyperparathyroidism
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 Workup of Hypercalcemia - Differential Diagnosis Algorithm High or Normal PTH: • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Normal PTH: • Hyperparathyroidism ... : Parathyroid adenoma ... Skeletal metastatic disease ... disorders, Paget's disease ... Granulomatous diseases
Hypocalcemia - Differential Diagnosis Algorithm • Low Serum Mg: GI losses, Renal losses, Alcoholism, Malnutrition, Drug-Induced
Elevated - Secondary Hyperparathyroidism ... Destruction of parathyroid ... , infiltrative disease ... sunlight • Other Causes ... Diagnosis #Algorithm #causes
Radial Fracture Due to Parathyroid Carcinoma- ...A plain radiograph of the left arm showed a diaphyseal
Fracture Due to Parathyroid ... diagnosis of primary hyperparathyroidism ... which is a rare cause ... of primary hyperparathyroidism ... radial #fracture #hyperparathyroidism
Causes of Hypocalcemia by Clinical Cause Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
by Clinical Cause ... illness - Secondary hyperparathyroidism ... levels Autoimmune disease ... removal Renal disease ... - Secondary hyperparathyroidism
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 Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Hyperparathyroidism ... • Secondary Hyperparathyroidism ... Phosphate Physical Symptoms ... pain Psychiatric Symptoms ... Secondary #Tertiary #pathophysiology
The pathophysiology of Primary hyperparathyroidism #Pathophysiology #PrimaryHyperparathyroidism #Parathyroid gland #Hyperparathyroidism
The pathophysiology ... of Primary hyperparathyroidism ... #Pathophysiology ... PrimaryHyperparathyroidism #Parathyroid ... gland #Hyperparathyroidism
Hypomagnesemia (Serum level < 1.7 mg/dL) Neuromuscular manifestations • Tremor, tetany, seizures • Weakness
Hypocalcemia • Hypoparathyroidism ... • Parathyroid ... Hypomagnesemia #Signs #Symptoms
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