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Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Parathyroid hormone–dependent ... Primary hyperparathyroidism ... Other humoral syndromes ... Hypercalcemia #Causes
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 Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... structure-related • Primary hyperparathyroidism ... disease • Tertiary hyperparathyroidism ... • Milk-alkali syndrome ... Hypercalcemia #Causes
Workup of Hypercalcemia - Differential Diagnosis Algorithm High or Normal PTH: • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Normal PTH: • Hyperparathyroidism ... : Parathyroid adenoma ... , Parathyroid carcinoma ... disease, Milk Alkali Syndrome ... disease, Viral Syndromes
Hypocalcemia - Differential Diagnosis Algorithm • Low Serum Mg: GI losses, Renal losses, Alcoholism, Malnutrition, Drug-Induced
Elevated - Secondary Hyperparathyroidism ... Inappropriately Normal/Low - Hypoparathyroidism ... Destruction of parathyroid ... sunlight • Other Causes ... Diagnosis #Algorithm #causes
Radial Fracture Due to Parathyroid Carcinoma- ...A plain radiograph of the left arm showed a diaphyseal
Fracture Due to Parathyroid ... diagnosis of primary hyperparathyroidism ... which is a rare cause ... of primary hyperparathyroidism ... radial #fracture #hyperparathyroidism
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Hyperparathyroidism ... • Secondary Hyperparathyroidism ... Phosphate Physical Symptoms ... pain Psychiatric Symptoms ... Secondary #Tertiary #pathophysiology
The pathophysiology of Primary hyperparathyroidism #Pathophysiology #PrimaryHyperparathyroidism #Parathyroid gland #Hyperparathyroidism
The pathophysiology ... of Primary hyperparathyroidism ... #Pathophysiology ... PrimaryHyperparathyroidism #Parathyroid ... gland #Hyperparathyroidism
Hypomagnesemia (Serum level < 1.7 mg/dL) Neuromuscular manifestations • Tremor, tetany, seizures • Weakness
Hypocalcemia • Hypoparathyroidism ... • Parathyroid ... Hypomagnesemia #Signs #Symptoms
Causes of Hypocalcemia by Clinical Cause Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
Causes of Hypocalcemia ... by Clinical Cause ... illness - Secondary hyperparathyroidism ... Malabsorption syndrome ... disease - Secondary hyperparathyroidism
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 Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
changes and may cause ... overload) Other Symptoms ... deficiency • Primary hyperparathyroidism ... • Secondary hyperparathyroidism ... Differential #Diagnosis #Pathophysiology
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