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diagnosis management differential infectiousdiseases treatment fuo immunology syndrome aids hematology hemophagocytic hlh humoral immune infection inflammatory lymphohistiocytosis origin pulmonary reconstitution
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
depend on the pathogen ... involved Pathogens ... - Pneumonitis (fever ... Fever, chills, lack ... edema Other Pathogens
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology Risk factors: - Low CD4 count - Disseminated OI -
Inflammatory Syndrome (IRIS ... ) - Pathophysiology ... factors: - Low CD4 ... Restoration of exuberant pathogen-specific ... #Pathophysiology
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Pathophysiology ... - Pathophysiology ... instability - New-onset fever ... Color #Targetoid #Algorithm
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
reactivation of latent pathogens ... • IRIS might ... • Symptoms: Fever ... • Symptoms: Fever ... patients with IRIS
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... Returning Traveler’ algorithm ... respective fungal pathogens ... udaygulati #FUO #Fever
Management Algorithm for Confusion - Substrate verification, glucose, oxygen checks - Toxidrome present - Focal findings on neurologic examination -
Management Algorithm ... examination - Fever ... examination, basic (CBC ... Delirium #Management #Algorithm
Cellular and humoral immune responses of the adaptive immune system. Activated T cells accomplish cellular immune
associated with CD4 ... or CD8, depending ... intracellular pathogen ... ImmuneResponses #immunology #pathophysiology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD) Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... comorbidities: • CBC ... respiratory viral pathogen ... #COPD #AECOPD #Algorithm
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
produced from pathogens ... present Ag to CD4 ... Opsonization: Abs coat pathogens ... Neutralization: Abs bind to pathogen ... Humoral #Immunity #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic Fever ... auto-reactive B and CD ... inflammation • Fever ... RheumaticFever #pathophysiology
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