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algorithm differential hypernatremia management syndrome 1 2 3 causes defects di diabetes epithelial gitelman hepatology hepatorenal high hrs hypokalemia inherited
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup Step #1 - Consider the history Step #2 - Assess
Hypernatremia Differential Diagnosis ... Algorithm - Diabetes Insipidus ... Workup Step ... Management #Algorithm #Sodium ... #nephrology #insipidus
Causes of Hypernatremia - Differential Diagnosis Inadequate water intake: • Lack of access to water Extrarenal hypotonic fluid
- Differential Diagnosis ... perspiration Renal ... Central diabetes insipidus ... #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Workup Algorithm ... mOsm/kg - Implies renal ... Euvolemic: Diabetes insipidus ... #nephrology #sodium
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Hypernatremia Diagnosis ... and Workup Step ... Repeat the sodium ... #Workup #Algorithm ... #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Epithelial Cells Renal ... of epithelial sodium ... Nephrogenic diabetes insipidus ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Diabetes Insipidus - Diagnosis Algorithm Tests: • Osmolality, Urine AND/OR • Osmolality, Serum or Plasma AND •
Diabetes Insipidus ... - Diagnosis Algorithm ... Plasma AND • Sodium ... Arginine Vasopressin Hormone ... #nephrology #differential
Primary Polydipsia Definition: Excessive volitional water intake Epidemiology: • 6-20% of patients with psychiatric disorders - Most commonly
: Diabetes Insipidus ... intoxication Initial Workup ... Urine Osm, Serum Sodium ... , Urine Sodium ... #management #nephrology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Syndrome (SPS) - Diagnosis ... Person Syndrome Pathophysiology ... antibody that works ... others (botox, sodium ... Management #treatment #neurology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... Gitelman #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
perfusion + ↑ renal ... Pathophysiology: ... • Urine sodium ... Syndrome #Hepatology #Nephrology ... #Diagnosis
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