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Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... injury • Gait is abnormal ... Causes: 1. ... reflexes: Areflexia ... #neurology #differential
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Lower motor neuron symptoms ... in deep tendon reflexes ... #differential #diagnosis ... #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
extensors of the arms (pyramidal ... Spasticity - Reflexes ... Bilateral signs and/or symptoms ... • Infectious causes ... #management #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
spine L1-L5 Symptoms ... - Emergency Causes ... Differential Diagnosis ... : • Spinal cord ... #causes #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... multiple spinal cord ... - Causes progressive ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cooled from the normal ... Cryofibrinogenemia Symptoms ... Cryofibrinogenemia Diagnosis ... cryoglobulins • Negative causes ... Biopsy: Typical pathologic
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Osteoclasts cause ... to breakage -> Pathologic ... or the spinal cord ... pathophysiology #diagnosis ... #signs #symptoms
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... depressed deep tendon reflexes ... bulbar muscles DIAGNOSIS ... than one after symptom ... #management #neurology
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
/ Hypovolemia NEUROLOGIC ... deficiency and hormone ... Hypothermia and Cold ... pathophysiology #diagnosis ... #signs #symptoms