16 results
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
over-secretion of growth hormone ... #Acromegaly #Signs ... Symptoms #Diagnosis #Endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
common), growth hormone ... ) the anterior hormones ... most essential hormones ... Signs / Symptoms ... #SideEffects #endocrinology
Woltman’s sign on Physical Exam

53-year-old man presented with fatigue and sensitivity to cold. A physical examination
Woltman’s sign on ... Woltman’s sign, ... deep-tendon reflex, is a neurologic ... Clinical #Video #Neurology ... #Endocrinology
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
action of thyroid hormones ... receptors for thyroid hormone ... clinical #video #neurology ... #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth Hormone ... (GH) Growth Hormone ... activates lipolysis Signs ... #FeedbackLoop #endocrinology
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
pituitary apoplexy) Hormone ... Hypopituitarism • Growth hormone ... Pituitary #Tumors #Signs ... Symptoms #Diagnosis #Endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Lhermitte’s sign ... Signs and symptoms ... objective evidence of neurologic ... adrenocorticotropin hormone ... diagnosis #management #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... renal bruit or signs ... of hormonal excess ... Vasculitis • Endocrinologic ... Neurologic disorders
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... of UMN and LMN signs ... of UMN and LMN signs ... EMG: LMN Signs in ... Lateral #Sclerosis #neurology