10 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
peripheral blood smear ... (CVID, WAS), (neurologic ... dysplasia on the smear ... Causes #Workup #hematology
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
Arthritis - 2020 ACR-EULAR ... joint) - 5 points Serology ... Arthritis #diagnosis #EULAR ... Classification #rheumatology
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
peripheral blood smear ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
pulmonary emboli, and ocular ... Biopsy: Typical pathologic ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... skin injury) • Neurologic ... spondyloarthritis • Ocular ... Leukemia, Lymphoma Ocular ... signs #symptoms #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... least 2 joints • Neurologic ... Erythematosus #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
affects the skin, neurologic ... cognitive impairment, neurologic ... ulcers, cutaneous, ocular ... Cogan syndrome: Ocular ... Differential #Diagnosis #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... Hypergammaglobulinemic macular ... Paraproteinemias #Hematology
Downbeat Nystagmus on Physical Exam

65 year old female with new walking difficulty and dizziness. Why downbeat
for intra-axial pathologies ... clinical #video #ocular ... ophthalmology #neurology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... by culture or serology ... osteoarticular, pulmonary, ocular ... Diagnosis: • Serology