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diagnosis management myelodysplastic rheumatology signs behcet chronic cll dermpath erythematosus gap globulin hodgkins infections infectiousdiseases lesions lupus lymphocytic lymphoma mds
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... EGPA • Solid cancers ... Vasculitis #dermpath #dermatology ... #manifestations ... #differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... Causes: - Idiopathic ... #diagnosis #dermatology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... : CNS manifestations ... - infiltrates (anemia ... CLL -> Invade Skin ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... Orange or Hep C Clinical ... Hepatomegaly • Skin ... • Neutropenia, anemia ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Manifestations: ... vasculitis) • Cutaneous ... ) Differential Diagnosis ... tears, Ischemia, Leukemia ... : monoclonal TNF-aIpha
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Disease Classification ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... Hodgkin lymphoma and leukemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Causes of Monoclonal ... gammopathy, and skin ... changes (POEMS syndrome ... gastric tumors • Hematology ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology
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