9 results
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... Autoimmune manifestations ... (dermatomyositis ... #differential # ... #oncology #clinical
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Cutaneous Manifestations ... Cold agglutinin disease ... #Cutaneous #manifestations ... #dermatology #skin ... #clinical
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... EGPA • Solid cancers ... #manifestations ... #pathology #lesions ... #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... permanent alopecia Differential ... , dermatomyositis ... • Non-autoimmune
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
causes: infections (cutaneous ... associated with cancers ... comparison #table #differential ... #diagnosis #dermatology ... #compared
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... presentation) • Cutaneous ... pts) Differential ... IgM monoclonal gammopathy
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
associated with autoimmune ... Manifestations ... Diagnosis: • + Clinical ... Biopsy: Typical pathologic ... Antiphospholipid syndrome
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
, and skin changes ... (POEMS syndrome ... Cirrhosis, ETOH, autoimmune ... ovarian tumors, lung cancers ... Gap #ProteinGap #differential
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... ) • Anti-Mi2 (skin ... • Anti-TIF1 (cancer-associated ... Extramuscular manifestations ... #rheumatology #differential