18 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic ... or negative - Smear ... C3 positive - Smear ... agglutination, rouleaux ... #diagnosis #hematology
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... evemariecrane #Rouleaux ... gammopathy #MGUS #Clinical ... #Pathology #Hematology ... #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
with extensive rouleaux ... PlasmaCell #leukemia #rouleaux ... #formation #Clinical ... #Smear #Hematology ... #Pathology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential Diagnosis ... Algorithm Signs ... Abnormal peripheral smear ... Hemolysis: • Autoimmune ... #Algorithm #hematology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
distinguished from “Rouleaux ... #Clinical #Pathology ... #Blood #Smear # ... Microscopy #Rouleaux ... #Formation #Hematology
Dermatofibroma 
 - Skin-colored to brown papule or nodule 
 - Firm, indurated texture 
 -
Dermatofibroma - Skin-colored ... Male - Dimple sign ... Dermatofibroma #Dermatology ... #Diagnosis #Benign ... #Clinical #Photo
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... arrow) Peripheral smear ... hemolytic #anemia #Hematology ... #Pathology #Smear
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
bleeding) • Rouleaux ... peripheral blood smear ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... • Peripheral smear ... immunophenotype Clinical ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
associated with autoimmune ... : • + Clinical ... Biopsy: Typical pathologic ... #rheumatology # ... hematology