6 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
) - Differential ... Drug-induced liver injury ... liver) • Non-hepatic ... Diagnosis #hepatology ... #transaminitis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
more specific for hepatic ... pathology (low ... #Cholestatic #Transaminitis ... #diagnosis #differential ... #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
2-5x normal - Hemolysis ... , NASH, Genetic ... #hepatology #LFTs ... #transaminitis ... #differential #diagnosis
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs ... ) vs Indirect (Hemolytic ... ≥ 2x ULN R Value ... #Elevation #Transaminitis ... #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
replaced by non-hepatic ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis ... #LFTs #RValue #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... : • Hepatic vein ... #hepatitis #differential ... #hepatology