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oncology algorithm blood causes hemeonc heparin hit induced product reactions activation adultonset anemia aplastic chronic cll coagulation dic differential disease
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Thrombocytopenic ... severe, ADAMTS13 deficiency ... #Purpura #management ... #treatment #rheumatology ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... effect following treatment ... following EtOH induced thrombocytopenia ... malignancy • Iron deficiency ... Algorithm #Causes #Hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
and initial management ... and to adjust treatment ... #Diagnosis #Management ... #Hematology #HIT ... Heparin #Induced #Thrombocytopenia
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
(HIT) - Diagnosis ... and Management ... Diagnosis: • ... #Diagnosis #Management ... #Treatment #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
thrombopoietin deficiency ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... mevalonate kinase deficiency ... Stills #Disease #diagnosis ... #management #treatment ... #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... with anemia or thrombocytopenia ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
infections/fevers • Thrombocytopenia ... , CTLA4 deficiency ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Cellular immune deficiency ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
leukopenia, anemia, and thrombocytopenia ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
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