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diagnosis rheumatology differential treatment algorithm hepatology dermatology syndrome causes workup oncology anemia gastroenterology clinical cirrhosis liver summary systemic table pathophysiology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... and Associated Diseases ... #Hematology #Diagnosis ... Basis of Disease
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
/ Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Anemia of Chronic Disease ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... Bite Cell RBC: G6PD ... Target Cell RBC ... differential #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... , Drugs, Liver Disease ... 3) Internal (RBC ... Electrolytes: Wilson's disease ... Differential #Diagnosis #hematology
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
directed donations) - RBC ... Hct of 70-80% - RBC ... ofplasma, a few RBC ... Contents #Volume #Hematology ... #Management #Table
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... disorders • Celiac disease ... Non malignant hematologic ... states • Non-hematologic ... Algorithm #Causes #Hematology
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... : Hemoglobin H disease ... Sickle cell, MDS #RBC ... Bodies #diagnosis #hematology
Dysmorphic Red Blood Cells on Electron Microscopy This eyeSCANdy image shows dysmorphic red blood cells from the
#Dysmorphic #RBCs ... SEM #clinical #pathology ... #hematology #nephrology
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 Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver Disease ... pathophysiology #pbc ... #psc #hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Cold agglutinins disease ... , Hemoglobin H disease ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... Algorithm #workup #hematology
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