49 results
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... shape, HbS induces RBC ... This leads to RBC ... #Complications ... #Hematology #Sequelae
hematopoiesis - leukocyte maturation tree

- Amy Chung, MD, MSc @AmyChung 

#hematopoiesis #leukocytes #maturation #tree #pathophysiology #Hematology
Amy Chung, MD, MSc ... maturation #tree #pathophysiology ... #Hematology #Progenitor ... #Cells #WBC #pathology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia 1) ... ↑ LDH • Anti-RBC ... TREAT AIHA 1 ... diagnosis #management #treatment ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... Low calcium • Treatment ... diagnosis #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
erythropoietin 1/ ... incidentally via CBC ... symptoms, signs, and complications ... • Treatment is ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Manifestations: 1) ... Vmphocytosis on routine CBC ... thrombocytopenia Complications ... : 1) Infection ... Leukemia #oncology #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... Female:Male 9:1 ... Pathophysiology ... • AMA titer 1: ... diagnosis #workup #hepatology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... - APC Grade 1 ... #Orthopedics #MSK ... #diagnosis #complications ... #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... symptoms, or> 1 ... Renal Failure Treatment ... diagnosis #management #hematology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
pain, Fever, ↑WBC ... Perforation) Pathophysiology ... Epidemiology: • #1 ... CT A/P: Assess complications ... 10 mg/kg IV x 1