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differential causes glomerular nephrotic proteinuria renal classification comparison nephritic pulmonary syndromes urine acute acutekidneyinjury ain aki blood bloodsmear borrelia casts
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
the patient has hematuria ... have glomerular hematuria ... (RBC casts or dysmorphic ... #Comparison #Algorithm ... #Nephrology #Diagnosis
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Diagnosis Framework ... basement membrane disease ... syndrome: • ... of glomerular disease ... causes #urology #nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(EM) Haematuria ... Haemolytic-uraemic syndrome ... Nephrotic syndrome ... #nephrology #pathology ... comparison #table #diagnosis
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC ... eosinophiluria, microscopic ... hematuria, mild ... #nephrology #diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... hematuria. ... RBC casts in urine ... #Proteinuria #Nephrology ... #Diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... Algorithm Red ... cells on urine microscopy ... • Thin GBM disease ... #Algorithm #Causes
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Algorithm Persistent ... • Fanconi's syndrome ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Dyspnea, Fever, Hematuria ... Differential Diagnosis ... polyangiitis, Microscopic ... #differential #diagnosis ... #nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... chronic kidney diseases ... glomerulonephritis • WBC ... #nephrology #interpretation ... #diagnosis
Chronic Diarrhea - Differential Diagnosis Algorithm Steatorrhea - Maldigestive • Pancreatic Insufficiency - Primary
- Differential Diagnosis ... Algorithm Steatorrhea ... Cancer • Microscopic ... (Screen with CBC ... #Algorithm
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