19 results
diagnosis causes oncology algorithm extravascular hemolysis thrombocytosis agglutinin aplastic arteritis ascorbicacid atlas calculation cbc chronic classification cold common cvid disease
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... ) (e.g. lupus, CLL ... G6PD deficiency) ... #diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... • Sickle cell ... circulation - Infections ... anemia • ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... , Disseminated intravascular ... key #diagnosis #differential ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider sickle cell ... #Anemia #Differential ... Algorithm #workup #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Index < 2: • Anemia ... anemia, Intrinsic ... anemia, G6PD deficiency ... Production #Index #hematology ... #anemia #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... , deficiency anemia ... Rebound effect from treatment ... Diagnosis #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... specifically: iron deficiency ... , hemolysis, hemorrhage ... myeloid leukemia (CML ... Diagnosis #Causes #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Clinical Presentation ... • Symptoms of anemia ... anemia • Cold ... younger pts) Differential ... #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... 5) Symptoms of anemia ... marrow failure with anemia ... Leukemia #oncology #hematology ... #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... -0/abstract BANDemia ... Degree of bandemia ... neutrophil #WBC #CBC #hematology ... #pathophysiology
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