15 results
causes oncology algorithm extravascular hemolysis thrombocytosis agglutinin calculation classification cold common cvid disease erythematosus fungal gca giantcell hemophagocytic heparin hit
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... G6PD deficiency) ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... • Sickle cell ... anemia • ... Differential #Diagnosis ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... , deficiency anemia ... : Chronic infections ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... specifically: iron deficiency ... , hemolysis, hemorrhage ... myeloid leukemia (CML ... #hematology #secondary
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
defects (e.g. sickle cell ... anemia, G6PD deficiency ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Clinical Presentation ... Diagnosis: • hemolytic ... younger pts) Differential ... the RBCs causing intravascular ... #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... immunophenotype Clinical ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... lymphoma (DLBCL, intravascular ... Cellular immune deficiency ... #management #treatment ... #summary #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
skin necrosis (at injection ... ♀, ↑Age, ESRD Pathophysiology ... D/c all heparin ... #Management #Treatment ... #Hematology #HemeOnc
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... and autoimmune hemolytic ... anemia) • Systemic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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