22 results
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver ... Disease (Cirrhosis ... ) - Complications ... #Cirrhosis #Complications ... management #summary #hepatology
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
& complications ... - Vitals - LFTs ... disease work up ... Calling #Referral #Hepatology ... #Gastroenterology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
2 V Vascular disease ... Abnormal renal/liver ... >2.3mg/dL) 1 Liver ... (cirrhosis, bilirubin ... AFib #Diagnosis #Hematology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... Phosphatase and Bilirubin ... initial insult Bilirubin ... #Hepatology #Pathophysiology ... #Diagnosis #LFTs
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
and Bleeding in Liver ... Disease Increased ... Bleeding #Clot #Cirrhosis ... #Pathophysiology ... #Hepatology #Liver
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... those with CLD (± cirrhosis ... disease, liver ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... disease: > 2 ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology ... transaminitis #LFTs
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
function: INR, bilirubin ... • Infiltrative diseases ... sarcoidosis) • Liver ... Veno-occlusive disease ... Diagnosis #causes #hepatology