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hematology management leukemia chronic classification differential hodgkins lymphoma signs acute aflp apml cancer differentiation disorders essential et fatty hemeonc liver
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... CLL Symptoms: • ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Diagnosis: • ... #Leukemia #diagnosis ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... thrombocytopenia Complications ... uw_IMresidency #CLL ... #Leukemia #oncology ... #hematology #hemeonc
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... pattern of spread, B symptoms ... Classification #pathophysiology ... #Hematology #Diagnosis
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
/ Complications ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
CRP Neuronal cell ... Sydenham's Chorea Lymphocytes ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... Differential Diagnosis ... #NonHodgkins #comparison ... #oncology #diagnosis ... #differential #hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... ↓Antithrombin Ill ... Monitor and Treat Complications ... Liver #Pregnancy #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... • Induce blast cell ... : >3 symptoms, or ... #management #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... ingestion • B symptoms ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... #oncology #management
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