7 results
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... staining (lg + complement ... MGPN • Complement ... pathway • C3 ... MPGN #nephrology #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... monitoring low-level glomerular ... or alternative complement ... pathways. ... testing #workup #diagnosis
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
activity of IFN pathway ... understanding of pathophysiology ... To propose new classifications ... IFN #signature #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... or alternative complement ... pathways. 6) SPEP ... #glomerular #disease ... #workup #diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... Labs/Diagnosis: ... • Low serum C4 complement ... Cryoglobulins #diagnosis ... #types #classification
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
light-chain ratio Diagnostic ... guide subtype classification ... tubulopathy) - Complement ... pathway activation ... #Significance #Diagnosis