5 results
diagnosis rheumatology cryoglobulinemia cryoglobulins gammopathy huv hypocomplementemic ifn igg4 interferon mgrs monoclonal renal signature significance types urticarial
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Complex Formation - Complement ... Pathway Activation ... Formation -> Vasculitis ... #HUV #Pathophysiology
The interferon (IFN) signature: what’s the point? How to use it in clinical practice? Characterizing activity of
activity of IFN pathway ... understanding of pathophysiology ... To propose new classifications ... signature #diagnosis #management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Through 2 Different Pathways ... • Low serum C4 complement ... • IgA vasculitis ... • Vasculitis ... diagnosis #types #classification
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
dysfunction PATHOPHYSIOLOGY ... aortitis, mimics vasculitis ... - ↑ IgE, ↓ complement ... • Classification ... IGG4 #Diagnosis #Management
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
guide subtype classification ... tubulopathy) - Complement ... pathway activation ... formation causing vasculitis
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