17 results
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
staining (lg + complement ... MGPN • Complement ... pathway • C3 ... (Dense deposit disease ... MPGN #nephrology #diagnosis
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
meningococcal disease ... response: The complement ... pathway is a non-specific ... alternative, or lectin pathway ... #pathophysiology
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Pharmacologic treatment algorithms ... Obstructive Lung Disease ... preferred treatment pathways ... Management #Pulmonary #COPD
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
BEARING CHILD PATHWAY ... suspicion of severe disease ... #Limping #NWB #Algorithm ... #Pathway #Child ... Peds #Pediatrics #Diagnosis
Arrhythmias - Differential Diagnosis Algorithm
May present as: palpitations, dizziness, syncope, chest discomfort
Cardiac Causes:
 - Structural
- Differential Diagnosis ... Algorithm May ... • Valve disease ... • Accessory pathway ... #Algorithm #causes
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... states Pathophysiology ... activate inflammatory pathways ... culture used to diagnose ... #rheumatology #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... permeability Diagnosis ... • Inflammatory Pathway ... cyclophosphamide • Ischemic Pathway
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... determine choice of pathway ... for users of the pathway ... alcohol-related liver disease ... LFTs #Abnormal #Algorithm
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
activity of IFN pathway ... understanding of pathophysiology ... classifications for diseases ... IFN #signature #diagnosis