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hematology oncology management differential mds myelodysplastic syndrome workup acidosis algorithm aplastic bowel chronic cll common cvid disorders elevation hypogammaglobulinemia ibs
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... ) Classification ... physical exam, CT ... Lymphoma Treatment ... #classification
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... Diagnosis: • ... • Neutropenia, anemia ... microglobulin Treatment ... PML leukemia, Hodgkin
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... Depletion Non-Hodgkin ... Responsive to Treatment ... Lymphoproliferative #Disorders #Classification
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... cytopenias (usually anemia ... Allogeneic stem cell ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... number of CD34+ cells ... Treatment: ... #oncology #hematology ... #diagnosis #management
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
Treatment: • Global ... Rifaximin- up to 3 courses ... intestinal epithelial cells ... and Hepatology ... #treatment
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... late adulthood • Diagnosis ... Chest CT: • Ground-glass ... autoimmune hemolytic anemia ... DDX - Other causes
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
e.g., uptake by cells ... perfusion - shock->treatments ... before beginning treatment ... 30mmHg) - Severe anemia ... #typeb #classification
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... including white blood cell ... #causes #hematology
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