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diagnosis differential algorithm clinical granular hematuria proteinuria urology atlas interpretation key management mbgc muddy muddybrown nephrotic renal rhabdomyolysis sediment syndrome
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
” Casts on Urine ... of mb granular casts ... Granular #MuddyBrown #Casts ... #Urine #Microscopy ... #Clinical #Nephrology
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... disease • “Muddy brown ... key #diagnosis #nephrology ... #casts
Muddy Brown Granular Casts three ways - Brightfield, Darkfield, Phase Contrast. Dr. Vipin Varghese @vipvargh #Muddy #Brown #Granular
Casts three ways ... #Granular #Casts ... #clinical #urine ... #microscopy #MBGC ... #nephrology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
• 1ml blood/liter ... hematuria: - RBC casts ... Dysmorphic RBC - Brown ... #urology #nephrology ... blood
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... casts are seen ... edgarvlermamd - Nephrology ... #Diagnosis #Nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... • "Muddy Brown ... #Urine #Microscopy ... #nephrology #interpretation
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... proteinuria, RBC casts ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... #blood #urine
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
arbitrarily defined as urine ... content [85].2>5 red blood ... cell/white cell casts ... Nephrocalcinosis causes ... nephrotic #syndrome #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Weakness - Dark urine ... UA positive for blood ... Cast formation: ... #treatment #nephrology
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